Picks · Oct 22, 2026
Buffalo Bills
AFC East
5-1Record
4-2ATS
5-1O/U
Next game
AFC East
- 1BillsBUF5-1—
- 2
PatriotsNE4-31.5 - 3
JetsNYJ2-43 - 4
DolphinsMIA0-54.5
Game odds
The best available line on each side of the next game.
Recent games
2026 betting trends
How the Buffalo Bills performed straight up, against the spread and on the total — at home, on the road, and in division play.
ATS4-267% cover rate
O/U5-183% over rate
| Split | W-L | ATS | O/U |
|---|---|---|---|
| Overall | 5-1 | 4-2 | 5-1 |
| Home | 2-1 | 2-1 | 2-1 |
| Away | 3-0 | 2-1 | 3-0 |
| Division | 0-1 | 0-1 | 1-0 |
| Conference | 3-1 | 2-2 | 3-1 |
Smart money
Futures
Season-long odds and how they’ve moved.
Championship
Super Bowl Winner+674Open +1000
Conference+350Open +550
Division Winner-287Open -110
Season outcomes
Make Playoffs
Yes-2500Open -360
No+1100Open +270
Season Wins 12.5
Over-105Open -139
Under-125Open +115
Latest news
Buffalo Bills coverage, plus the league-wide picks they appear in.