49ers look to break poor ATS streak as favorites against the Lions
Wed, Sep 8th 8:31pm EDT
The 49ers are -7.5 point road favorites, per BettingPros consensus odds. San Francisco is the only road team favored by more than 4.5 points in Week 1. The 49ers are 7-3 ATS in their last ten season openers, and are 5-2 ATS In their last seven games in September. Conversely, the Lions are 7-3 ATS in their last ten September games, but are 5-11 ATS in their last 16 games on fieldturf.