49ers look for rare winning streak as favorites against the Eagles
Wed, Sep 15th 4:19pm EDT
The 49ers are -175 moneyline road favorites, per BettingPros consensus odds. San Francisco's only straight up win in their last six games as favorites was their Week 1 win against the Lions. However, they had to hold on for dear life for that victory, as Detroit clawed back from a 41-17 deficit and had a chance to tie late after cutting the lead to 41-33. Considering the Eagles are just 2-9 in their last 11 games in September, that trend supports a 49ers victory in Week 2.